Wall Street ends flat as wary investors stay defensive

NEW YORK (Reuters) - Stocks were little changed on Thursday as the prospect of a drawn-out battle over impending tax and spending changes made investors wary of getting into the water, while retailer Wal-Mart tumbled after disappointing sales.


The S&P 500 is down nearly 2 percent for the week, adding to last week's selloff and eroding more of the market's gains for the year.


What had looked like a stellar 2012 for stocks has turned into merely an average year, and as 2012 draws to a close, investors are becoming more inclined to protect the gains they have.


The worry is the economy could contract again if no deal is reached in Washington to avoid the "fiscal cliff" - large, automatic budget cuts and tax hikes that begin to take effect in the new year.


Combined with the euro zone debt crisis, the uncertain outlook for corporations makes it hard to know how much a stock is worth, said Alan Lancz, president of Alan B. Lancz & Associates in Toledo, Ohio.


"Valuation is going to be uncertain because you don't know what the growth will be," said Lancz. "That is definitely not a good scenario for someone to step up to the plate and do a lot of buying."


The euro zone relapsed into its second recession since 2009 in the third quarter as the region was hurt by its debt problems.


Wal-Mart fell 3.6 percent to $68.72 and was the biggest drag on the Dow as frugal consumers hurt the company's quarterly sales.


Investors will be watching Friday's meeting at the White House between President Barack Obama and Republican and Democratic leaders of Congress over deficit reduction for any sign the two sides are moving closer.


The memory of last year's political impasse over raising the debt ceiling has also made analysts nervous.


"(There is) uncertainty of whether we're going to have a functioning government going forward. That is a weight that sits on markets right now," said Troy Logan, managing director and senior economist at Warren Financial Service in Exton, Pennsylvania.


Even if the economy avoids an outright recession, there are fears a lengthy political dispute could sap business investment and consumer spending.


The Dow Jones industrial average <.dji> slipped 28.49 points, or 0.23 percent, to 12,542.46. The Standard & Poor's 500 Index <.spx> lost 2.16 points, or 0.16 percent, to 1,353.33. The Nasdaq Composite Index <.ixic> was off 9.87 points, or 0.35 percent, to 2,836.94.


The S&P 500 sunk to a 3 1/2-month closing low and was well below its 200-day moving average, which it pierced last week.


Data on Thursday showed new claims for unemployment benefits surged last week, while factory activity in the mid-Atlantic region unexpectedly shrank in November as the economy felt the effects of superstorm Sandy.


A flare-up in violence in the Middle East added to market unease as Israeli warplanes bombed targets in and around Gaza city for a second day, while two rockets fired from the Gaza Strip targeted Tel Aviv.


Apple Inc shares dragged the Nasdaq lower, falling 2.1 percent to $525.62 and down about 25 percent since September's high.


Also in the tech sector, shares of Dell Inc fell in after-hours trading after it reported revenue that was shy of Wall Street's expectations. Dell was down 2.2 percent at $9.35.


Target Corp bucked the trend, rising 1.7 percent to $62.44 after it reported a profit that beat expectations.


Volume was roughly 7.26 billion shares on the New York Stock Exchange, the Nasdaq and the NYSE MKT, topping the year-to-date average daily closing volume of around 6.5 billion.


Decliners outnumbered advancers on the NYSE by 2,069 to 975 on the New York Stock Exchange. Decliners also had the upper hand on the Nasdaq, outpacing advancers 1,506 to 948.


(Editing by Kenneth Barry)


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Egypt PM to visit Gaza in support of Hamas against Israel

GAZA (Reuters) - Egypt's prime minister prepared to visit the Gaza Strip on Friday in an unprecedented display of solidarity with Hamas militants embroiled in a new escalation of conflict with Israel that risks spiraling into all-out war.


Two rockets from Gaza crashed near Tel Aviv in the first such attack on Israel's commercial capital in 20 years. One fell into the Mediterranean Sea and the other in an uninhabited part of one of the Tel Aviv suburbs south of the city.


Two days of Israeli air strikes have killed 19 Palestinians, including seven militants and 12 civilians, among them six children and a pregnant woman. A Hamas rocket killed three Israelis in the town of Kiryat Malachi on Thursday morning.


The latest upsurge in the long-running conflict came on Wednesday when Israel killed Hamas' military mastermind, Ahmed Al-Jaabari, in a precision air strike on his car. Israel then began shelling the coastal enclave from land, air and sea.


Israel says its offensive responded to increasing missile salvoes from Gaza. Its bombing has not yet reached the saturation level seen before it last invaded Gaza in 2008, but Israeli officials have said a ground assault remains possible.


The Gaza conflagration has stoked the flames of a Middle East ablaze with two years of Arab popular revolution and a civil war in Syria that threatens to spread further afield.


Israeli warplanes bombed targets in and around Gaza City, rattling tall buildings. In a hint of escalation, the spokesman for Israel's military said it had received the green light to call in up to 30,000 reserve troops.


Egypt's new Islamist President, Mohamed Mursi, viewed by Hamas as a protector, led a chorus of denunciation of the Israeli strikes by allies of the Palestinians.


Mursi's prime minister, Hisham Kandil, is to visit Gaza on Friday with other Egyptian officials in a show of support for the enclave, an Egyptian cabinet official said. Israel promised the delegation would come to no harm.


An Egyptian government source, speaking on condition of anonymity, said officials accompanying Kandil would explore the possibility of brokering a ceasefire.


Mursi faces domestic pressure to act tough. But Egypt gets $1.3 billion a year in U.S. military aid and looks to Washington for help with its ailing economy, constraining Mursi despite his need to show Egyptians that his policies differ from those of his U.S.-backed predecessor Hosni Mubarak.


TEL AVIV TARGETED


Air raid sirens sent residents running for shelter in Tel Aviv, a Mediterranean city that has not been hit by a rocket since the 1991 Gulf War, when it was targeted by Saddam Hussein's Iraq.


The Tel Aviv metropolitan area is home to more than 3 million people, more than 40 percent of Israel's population. "This escalation will exact a price that the other side will have to pay," Barak said in a television broadcast shortly after the strike.


But an Israeli cabinet statement on Wednesday spoke only of "improving" national security - acknowledgement that the Jewish state has no illusions about crushing the militants once and for all.


Speaking at the same time in Gaza, Hamas leader Ismail Haniyeh urged Egypt to do more to help the Palestinians.


"We call upon the brothers in Egypt to take the measures that will deter this enemy," the Hamas prime minister said.


The resurgent conflict will be the biggest test yet of Mursi's commitment to Egypt's 1979 peace treaty with Israel, which the West views as the bedrock of Middle East peace.


Cairo recalled its ambassador from Israel on Wednesday. Israel's ambassador left Cairo on what was called a routine home visit; Israel said its embassy would remain open.


The Muslim Brotherhood, which brought Mursi to power in an election after the downfall of Hosni Mubarak, has called for a "Day of Rage" in Arab capitals on Friday. The Brotherhood is seen as the spiritual mentor of Hamas.


The Israeli army said 300 targets were hit in Gaza, including more than 130 militant rocket launchers. It said more than 270 rockets had struck Israel since the start of the operation, with its Iron Dome interceptor system shooting down more than 130 rockets bound for residential areas.


Expecting days or more of fighting and almost inevitable civilian casualties, Israeli warplanes dropped leaflets in Gaza advising residents to stay away from Hamas and other militants.


DIPLOMATIC EFFORTS


United Nations diplomats said Secretary General Ban Ki-moon would head to Israel and Egypt next week to try to mediate a ceasefire, although they gave no further details.


The United States has asked countries that have contact with Hamas to urge the Islamist movement to stop its recent rocket attacks from Gaza, a White House adviser said.


"We've ... urged those that have a degree of influence with Hamas, such as Turkey and Egypt and some of our European partners, to use that influence to urge Hamas to de-escalate," Ben Rhodes, deputy national security adviser, said in a conference call with reporters.


French President Francois Hollande began talks with Israeli Prime Minister Benjamin Netanyahu and other world leaders in an attempt to avert an escalation of violence in the Gaza Strip, Prime Minister Jean-Francois Ayrault said.


British Prime Minister David Cameron spoke to Netanyahu too, saying Hamas bore the principal responsibility for the crisis.


Israel's sworn enemy Iran, which supports and arms Hamas, condemned the Israeli offensive as "organized terrorism."


Lebanon's Iranian-backed Shi'ite Muslim militia Hezbollah, which has its own rockets aimed at the Jewish state, denounced strikes on Gaza as "criminal aggression," but held its fire.


The Organisation of Islamic Cooperation condemned Israel's action.


(Additional reporting by Louis Charbonneau at the United Nations, Writing by Ori Lewis in Jerusalem, Editing by Mark Heinrich and Todd Eastham)


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Xbox Live Celebrates 10 Years of Connecting Gamers
















Thursday marks the tenth anniversary of Xbox Live, Microsoft’s online gaming platform for the Xbox and the Xbox 360.


[More from Mashable: Steve Ballmer Hints at Microsoft Building More Hardware]













For the last decade, Xbox Live has offered both a marketplace and online play space for gamers. It started in 2002 on Microsoft‘s original Xbox console; Xbox spokeperson Larry Hryb, better known as Major Nelson, said it launched with games like Ghost Recon, MechAssault and NFL Fever.


Now Xbox Live serves as a complete entertainment package for the Xbox 360. Players can still compete online and connect with others, but can also access all kinds of other services through their Xbox 360 as the console moves to position itself as a living room centerpiece. Streaming services like Netflix, Hulu Plus, Pandora, HBO Go, ESPN and NBA Live, as well as on-demand movies from Zune. During this year’s election, Xbox Live offered full access to the debates and election coverage, thanks to a partnership with NBC.


[More from Mashable: New ‘Grand Theft Auto V’ Trailer Takes Game Violence to the Next Level [VIDEO]]


There are about 30 million Xbox Live subscribers, each with their own unique gamertag. Xbox Live was instrumental in the widespread adoption of achievements on games, which players unlocked for completing different in-game challenges. According to Hyrb’s Twitter account, gamers have unlocked 14.5 billion achievements in the past decade.


Xbox Live is the only online network on consoles that charges its users, at $ 60 a pop for a 12-month subscription.


To celebrate today’s anniversary, some long-time Xbox Live subscribers are receiving special edition Xbox 360s, according to Hyrb’s Twitter feed. Hyrb is also giving out one-year subscriptions to Xbox Live on his Twitter all day Thursday.


Do you have fond memories of playing Xbox Live in the past decade? Please share them with us in the comments.


1. Triforce Lamp


Know a Zelda fan in need of some power, wisdom and courage? This beautiful wood and acrylic lamp can be hung or shelved. The pixelated carvings on each side warm the room with dappled light. Price: $ 95.00


Click here to view this gallery.


Image courtesy Rodrigo Denúbila, Flickr.


This story originally published on Mashable here.


Gaming News Headlines – Yahoo! News



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Cesar Millan Reveals: I Attempted Suicide















11/15/2012 at 06:30 PM EST







Cesar Millan with dog Daddy


Meredith Jenks


It seemed Cesar Millan had been on top of the world, but then it all came crashing down.

In 2010, the trainer and television personality known as the Dog Whisperer was working with celebrity clients, had a hit show and was becoming an international advocate for bully breeds.

Millan, 43, was dealt his first loss when Daddy, the 16-year-old pit bull who had been Millan's best example of a "calm, submissive" dog, died in February.

Then, in June of that year, Millan learned that his wife of 16 years, Ilusion Millan, had filed for divorce.

"I was at the lowest level I had ever been emotionally and psychologically," Millan wrote on his blog in August of this year.

So low, in fact, that he attempted suicide, a revelation Millan makes in Cesar Millan: The Real Story, a documentary airing on Nat Geo Wild on Nov. 25.

"Daddy was my Tibet, my Himalaya, my Gouda, my Buddha, my source of calmness," Millan tells the Associated Press.

After surviving the overdose, Millan opted for work, exercise and affection over antidepressants. His recovery progressed further when he met Jahira Dar, a woman Millan calls "the one."

He plans to propose soon. "I am a traditional guy, so I like to do the whole parent thing," Millan said. "I know they are going to say yes, but I like the whole Cinderella story."

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Diabetes rates rocket in Oklahoma, South

NEW YORK (AP) — The nation's diabetes problem is getting worse, and the biggest jump over 15 years was in Oklahoma, according to a new federal report issued Thursday.

The diabetes rate in Oklahoma more than tripled, and Kentucky, Georgia and Alabama also saw dramatic increases since 1995, the study showed.

The South's growing weight problem is the main explanation, said Linda Geiss, lead author of the report by the Centers for Disease Control and Prevention study.

"The rise in diabetes has really gone hand in hand with the rise in obesity," she said.

Bolstering the numbers is the fact that more people with diabetes are living longer because better treatments are available.

The disease exploded in the United States in the last 50 years, with the vast majority from obesity-related Type 2 diabetes. In 1958, fewer than 1 in 100 Americans had been diagnosed with diabetes. In 2010, it was about 1 in 14.

Most of the increase has happened since 1990.

Diabetes is a disease in which the body has trouble processing sugar; it's the nation's seventh leading cause of death. Complications include poor circulation, heart and kidney problems and nerve damage.

The new study is the CDC's first in more than a decade to look at how the nationwide boom has played out in different states.

It's based on telephone surveys of at least 1,000 adults in each state in 1995 and 2010. Participants were asked if a doctor had ever told them they have diabetes.

Not surprisingly, Mississippi — the state with the largest proportion of residents who are obese — has the highest diabetes rate. Nearly 12 percent of Mississippians say they have diabetes, compared to the national average of 7 percent.

But the most dramatic increases in diabetes occurred largely elsewhere in the South and in the Southwest, where rates tripled or more than doubled. Oklahoma's rate rose to about 10 percent, Kentucky went to more than 9 percent, Georgia to 10 percent and Alabama surpassed 11 percent.

An official with Oklahoma State Department of Health said the solution is healthier eating, more exercise and no smoking.

"And that's it in a nutshell," said Rita Reeves, diabetes prevention coordinator.

Several Northern states saw rates more than double, too, including Washington, Idaho, Montana, Wyoming, South Dakota, Minnesota, Missouri, Ohio and Maine.

The study was published in CDC's Morbidity and Mortality Weekly Report.

___

Associated Press writer Ken Miller in Oklahoma City contributed to this report.

___

Online:

CDC report: http://tinyurl.com/cdcdiabetesreport

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Wall Street drops on deficit, Middle East concerns

NEW YORK (Reuters) - Stocks slid on Wednesday with declines accelerating after President Barack Obama set up a drawn-out fight over the fiscal cliff when he stuck to his pledge to raise taxes on the wealthy, and as violence increased in the Middle East.


Obama, in his first press conference since re-election, held to his position that marginal tax rates will have to rise to tackle the nation's deficits.


With talks over solving the U.S. "fiscal cliff" in early stages, investors are reacting to the uncertainty by shedding positions.


"I think we will have a last-minute cliffhanger solution," said Michael Cheah, portfolio manager at SunAmerica Asset Management in Jersey City, New Jersey, about a deal to avoid the so-called cliff.


"In the meantime, the market is going to get punched every day."


Without a deal, a series of mandated tax hikes and spending cuts will start to take effect early next year that could push the U.S. economy into a recession.


Taxes on capital gains and dividends could rise as part of the negotiations, pushing investors to sell this year and pay lower taxes on their gains.


Adding to the selling pressure, Israel launched a major offensive against Palestinian militants in Gaza, killing the military commander of Hamas in an air strike and threatening an invasion of the enclave. Egypt said it recalled its ambassador from Israel in response.


"We know Europe's in trouble, China's slowing down ... and now you've got the Middle East flaring up again. It's all hitting at once, and obviously, the market is taking a 'sell first, ask questions later' approach," said Ryan Detrick, senior technical strategist at Schaeffer's Investment Research in Cincinnati.


Industrial shares led the decline, dragged lower in part by a 1 percent spike in crude prices after the Israeli offensive on Gaza. The S&P industrial sector index <.gspi> fell 2.5 percent.


Wall Street had opened higher after Dow component Cisco Systems Inc reported first-quarter earnings and revenue late Tuesday that beat expectations, driving its stock up 4.8 percent to $17.66. But the positive momentum was short-lived.


The Dow Jones industrial average <.dji> fell 185.23 points, or 1.45 percent, to 12,570.95 at the close. The S&P 500 <.spx> dropped 19.04 points, or 1.39 percent, to 1,355.49. The Nasdaq Composite <.ixic> lost 37.08 points, or 1.29 percent, to 2,846.81.


Both the Dow industrials and the Nasdaq ended at their lowest levels since late June.


The S&P 500 has fallen 5.1 percent in the six sessions since election night. Wednesday marked the benchmark index's lowest close since July 25.


The Russell 2000 <.rut> tumbled 2 percent. The Dow Jones Transportation average <.djt> slid 2.6 percent. FedEx Corp shares dropped 3.7 percent to $87.12. Bank of America shares lost 3.6 percent to $8.99.


In contrast, Facebook shares jumped 12.6 percent to $22.36 as investors were relieved that expiring trading restrictions on a huge block of shares did not trigger an immediate wave of insider selling.


Teen clothing retailer Abercrombie & Fitch Co jumped 34.4 percent to $41.92 after the company reported unexpectedly improved third-quarter results and a full-year outlook that exceeded Wall Street's forecasts.


About 7.53 billion shares changed hands on the New York Stock Exchange, the Nasdaq and NYSE MKT, more than the daily average so far this year of about 6.51 billion shares.


On the NYSE, decliners outnumbered advancers by a ratio of almost 9 to 1. On the Nasdaq, about four stocks fell for every one that rose.


(Reporting by Rodrigo Campos; Additional reporting by Steven C. Johnson and Leah Schnurr; Editing by Jan Paschal)


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Israel hammers Hamas in Gaza offensive

GAZA (Reuters) - Israel launched a major offensive against Palestinian militants in Gaza on Wednesday, killing the military commander of Hamas in an air strike and threatening an invasion of the enclave that the Islamist group vowed would "open the gates of hell".


The onslaught shattered hopes that a truce mediated on Tuesday by Egypt could pull the two sides back from the brink of war after five days of escalating Palestinian rocket attacks and Israeli strikes at militant targets.


Operation "Pillar of Defence" began with a surgical strike on a car carrying the commander of the military wing of Hamas, the Iranian-armed Islamist movement which controls Gaza and dominates a score of smaller armed groups.


Within minutes of the death of Ahmed Al-Jaabari, big explosions shook Gaza as the Israeli air force struck at selected targets just before sundown, blasting plumes of smoke and debris high above the crowded city.


Panicking civilians ran for cover and the death toll mounted quickly. Ten people including three children were killed, the health ministry said, and about 40 were wounded. Also among the dead were an 11-month-old baby and a woman pregnant with twins.


Army tanks shelled border areas of Gaza in south and the Israeli navy shelled a Hamas security position from the sea.


Hamas stuck back, firing at least four Grad rockets at the southern city of Beersheba in what it called its initial response. Israel reported damage but no casualties. Its 'Iron Dome' interceptor defence knocked out a dozen rockets in flight.


The escalation in Gaza came in a week when Israel fired at Syrian artillery positions it said had fired into the Israeli-annexed Golan Heights amid a civil war in Syria that has brought renewed instability to neighboring Lebanon.


Egypt, whose new Islamist government pledged to honor the 1979 peace treaty with Israel, condemned the raids as a threat to regional security, recalled its ambassador from Israel and called for an emergency session of the U.N. Security Council.


Egyptian President Mohamed Mursi's predecessor Hosni Mubarak twice withdrew his ambassador, with no lasting effect. But Israel will be watching for signs of a more aggressive approach by the Islamist leader that could imperil their ties.


Mursi has said of the Palestinians that "our blood is their blood" and Egypt may not "accept what was accepted before".


Russia called for an end to the raids. Arab League foreign ministers planned to meet on Saturday to discuss the crisis.


DOZENS OF TARGETS


A second Gaza war has loomed on the horizon for months as waves of Palestinian rocket attacks and Israeli strikes grew increasingly more intense and frequent.


Israel's Operation Cast Lead in 2008-2009 began with a week of air attacks and shelling, followed by a land invasion of the blockaded coastal strip, sealed off at sea by the Israeli navy. Some 1,400 Palestinians were killed and 13 Israelis died.


The Israel Defence Forces said it had targeted dozens of Hamas's medium range (up to 40km) underground rocket launch and infrastructure sites in Wednesday's strikes.


"This has significantly damaged the rocket launch capabilities as munitions warehouses owned by Hamas and other terror organizations were targeted. In addition, Israeli Navy soldiers targeted several Hamas terror sites stationed along the shoreline of the Gaza Strip," it said in a statement.


The Hamas internal security headquarters in southern Gaza was destroyed. There were no injuries because it had been evacuated. After dark, Gaza looked like a ghost city, with no traffic and no people in the streets, no shops open, no electric lights on.


KILLED IN HIS CAR


Hamas said Jaabari, who ran the organization's armed wing, Izz el-Deen Al-Qassam, died along with a Hamas photographer when their car was blown apart by an Israeli missile.


The charred wreckage of a car could be seen belching flames, as emergency crews picked up what appeared to be body parts.


Israel confirmed it had carried out the attack and announced there was more to come. Reuters witnesses saw Hamas security compounds and police stations blasted apart.


"Today we relayed a clear message to the Hamas organization and other terrorist organizations," Prime Minister Benjamin Netanyahu said. "And if there is a need, the IDF (Israel Defence Forces) is prepared to broaden the operation. We will continue to do everything in order to protect our citizens."


Immediate calls for revenge were broadcast over Hamas radio.


"The occupation has opened the gates of hell," Hamas's armed wing said. Smaller groups also vowed to strike back.


"Israel has declared war on Gaza and they will bear the responsibility for the consequences," Islamic Jihad said.


Southern Israeli communities within rocket range of Gaza were on full alert, and schools were ordered closed for Thursday. About one million Israelis live in range of Gaza's relatively primitive but lethal rockets, supplemented in recent months by longer-range, more accurate systems.


"The days we face in the south will, in my estimation, prove protracted," Brigadier-General Yoav Mordechai, Israel's chief military spokesman, told Channel 2 TV.


The Israeli cabinet gave preliminary authorization for the mobilization of military reserves if required, Netanyahu's office said.


Asked if Israel might send in ground forces, Mordechai said: "There are preparations, and if we are required to, the option of an entry by ground is available."


OBAMA BRIEFED


Israeli President Shimon Peres briefed U.S. President Barack Obama on the operation, Peres's office said. He told Obama that Jaabari was a "mass-murderer" and his killing was Israel's response to Palestinian rocket attacks from Gaza.


"Israel is not interested in stoking the flames, but for the past five days there has been constant missile fire at Israel and mothers and children cannot sleep quietly at night," said Peres, who visited the border town of Sderot earlier.


In the flare-up that was prelude to Wednesday's offensive, more than 115 missiles were fired into southern Israel from Gaza and Israeli planes launched numerous strikes.


Seven Palestinians, three of them gunmen, were killed. Eight Israeli civilians were hurt by rocket fire and four soldiers wounded by an anti-tank missile.


The leader of Hamas in the Gaza Strip, Ismail Haniyeh, called on Arab states, especially Egypt, to halt the assault. The six-nation Gulf Cooperation Council said the U.N. Security Council should put pressure on Israel to stop its attacks.


Israel holds a general election on January 22 and Netanyahu has pledged to retaliate harshly against Hamas. But Israel is also wary of the reaction from Mursi's Egypt, whose ruling Muslim Brotherhood is the spiritual mentor of Hamas.


Hamas has been emboldened by its rise to power, viewing Mursi as a "safety net" who will not permit a second Israeli thrashing of Gaza, home to 1.7 million Palestinians.


Hamas is also supported by Iran, which Israel regards as a rising threat to its own existence due to its nuclear program.


Helped by the contraband trade through tunnels from Egypt, Gaza militias have smuggled in longer-range rockets.


But their estimated 35,000 Palestinian fighters are still no match for Israel's F-16 fighter-bombers, Apache helicopter gun ships, Merkava tanks and other modern weapons systems in the hands of a conscript force of 175,000, with 450,000 in reserve.


(Additional reporting by Dan Williams, Crispian Balmer and Ori Lewis in Jerusalem; Writing by Douglas Hamilton; Editing by Giles Elgood)


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Verizon says 1.4 million customers back on its fiber optic network
















(Reuters) – Verizon Communications said fiber optic services have been restored to more than 1.4 million customers hurt by Hurricane Sandy.


The provider of telephone, Internet and television services said on November 1 that it may take another two weeks to restore telecommunication services for its customers after flooding and power outages knocked out services.













The company said it completed 364,000 repairs across the mid-Atlantic and northeast regions.


Verizon said it will provide credits for landline customers and fix equipment damaged due to the hurricane.


Verizon shares were up at $ 42.39 after the bell on Wednesday. They closed at $ 42.24 on the New York Stock Exchange.


(Reporting By Pallavi Ail in Bangalore; Editing by Maju Samuel)


Internet News Headlines – Yahoo! News



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Hope Solo Weds Jerramy Stevens Amid Assault Allegations?















11/14/2012 at 06:35 PM EST







Jerramy Stevens and Hope Solo


NFL/Getty; Jeff Vinnick/Getty


One day after former Seattle Seahawks tight end Jerramy Stevens was arrested on suspicion of assaulting his fiancée, U.S. women's soccer team goalkeeper Hope Solo, the pair reportedly tied the knot.

"Confirmed," Sportsradio 950 AM and 102.9 FM radio host Dave Mahler Tweeted on Tuesday. "Jerramy Stevens and Hope Solo were married tonight. Events of yesterday morning didn't change plans."

The pair, who had only been dating for about two months, applied for a marriage license last Thursday. According to court documents, the athletes were arguing over whether to wed in Florida or Washington State.

Stevens, 33, was reportedly released from custody by a Kirkland, Wash., Municipal Court judge on Tuesday after determining there wasn't enough evidence to hold the former football star.

All of the former Dancing with the Stars contestant's social media pages have gone silent since Nov. 6., and calls to her rep have not been returned.

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New gene triples risk for Alzheimer's disease

Scientists have identified a new gene variant that seems to strongly raise the risk for Alzheimer's disease, giving a fresh target for research into treatments for the mind-robbing disorder.

The problem gene is not common — less than 1 percent of people are thought to have it — but it roughly triples the chances of developing Alzheimer's compared to people with the normal version of the gene. It also seems to harm memory and thinking in older people without dementia.

The main reason scientists are excited by the discovery is what this gene does, and how that might reveal what causes Alzheimer's and ways to prevent it. The gene helps the immune system control inflammation in the brain and clear junk such as the sticky deposits that are the hallmark of the disease. Mutations in the gene may impair these tasks, so treatments to restore the gene's function and quell inflammation may help.

"It points us to potential therapeutics in a more precise way than we've seen in the past," said Dr. William Thies, chief medical and scientific officer of the Alzheimer's Association, which had no role in the research. Years down the road, this discovery will likely be seen as very important, he predicted.

It is described in a study by an international group published online Wednesday by the New England Journal of Medicine.

About 35 million people worldwide have dementia, and Alzheimer's is the most common type. In the U.S., about 5 million have Alzheimer's. Medicines such as Aricept and Namenda just temporarily ease symptoms. There is no known cure.

Until now, only one gene — ApoE — has been found to have a big impact on Alzheimer's risk. About 17 percent of the population has at least one copy of the problem version of this gene but nearly half of all people with Alzheimer's do. Other genes that have been tied to the disease raise risk only a little, or cause the less common type of Alzheimer's that develops earlier in life, before age 60.

The new gene, TREM2, already has been tied to a couple other forms of dementia. Researchers led by deCODE Genetics Inc. of Iceland honed in on a version of it they identified through mapping the entire genetic code of more than 2,200 Icelanders.

Further tests on 3,550 Alzheimer's patients and more than 110,000 people without dementia in several countries, including the United States, found that the gene variant was more common in Alzheimer's patients.

"It's a very strong effect," raising the risk of Alzheimer's by three to four times — about the same amount as the problem version of the ApoE gene does, said Dr. Allan Levey, director of an Alzheimer's program at Emory University, one of the academic centers participating in the research.

Researchers also tested more than 1,200 people over age 85 who did not have Alzheimer's disease and found that those with the variant TREM2 gene had lower mental function scores than those without it. This adds evidence the gene variant is important in cognition, even short of causing Alzheimer's.

"It's another piece in the puzzle. It suggests the immune system is important in Alzheimer's disease," said Andrew Singleton, a geneticist with the National Institute on Aging, which helped pay for the study.

One prominent scientist not involved in the study — Dr. Rudolph Tanzi, a Harvard Medical School geneticist and director of an Alzheimer's research program at Massachusetts General Hospital — called the work exciting, but added a caveat.

"I would like to see more evidence that this is Alzheimer's" rather than one of the other dementias already tied to the gene, Tanzi said. Autopsy or brain imaging tests can show whether the cases attributed to the gene variant are truly Alzheimer's or misdiagnosed, he said.

___

Online:

Medical journal: http://www.nejm.org

Alzheimer's info: http://www.alzheimers.gov

Alzheimer's Association: http://www.alz.org

___

Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP

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